Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon
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منابع مشابه
Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon.
Actions of lubiprostone, a selective type-2 chloride channel activator, on mucosal secretion were investigated in guinea pig small intestine and colon. Flat-sheet preparations were mounted in Ussing flux chambers for recording short-circuit current (Isc) as a marker for electrogenic chloride secretion. Lubiprostone, applied to the small intestinal mucosa in eight concentrations ranging from 1-3...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2009
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.90447.2008